What this medication does

Norethindrone is a progestin (a hormone similar to progesterone). When taken before your period starts, it can help delay menstrual bleeding until you stop the medication.

This medication is meant for short-term cycle delay only. It does not permanently change your cycle.

How to take it

• Take 1 tablet by mouth 3 times daily with a meal (breakfast, lunch, and dinner).
• Start the medication at least 3 days before your expected period begins.
• Continue daily dosing for up to 10 days.
• Your period usually returns within 2–3 days after stopping.
• If bleeding has already started, norethindrone wil NOT be effective at stopping it.

Tip: For best results, take doses at evenly spaced times each day.

What to expect

• Light spotting or breakthrough bleeding
• Bloating or mild cramping
• Breast tenderness
• Headache or nausea
• Mood changes or irritability

These effects are usually temporary and resolve after stopping the medication.

Important warnings

• Norethindrone may slightly increase the risk of a blood clot, especially in people with clotting risk factors.
• Do not use this medication if you have a history of blood clots, stroke, certain cancers, or severe liver disease unless specifically cleared by your clinician.
• Some medications and supplements may reduce effectiveness (including certain seizure medications, migraine treatments, and herbal products).
• This medication is not reliable contraception and does not prevent pregnancy.
• Do not use period delay medication more than once every 3 months unless advised.

Emergency care

Seek emergency medical care immediately if you develop: chest pain, shortness of breath, leg swelling or pain, sudden severe headache, vision changes, weakness on one side, or severe heavy bleeding.

For mental health emergencies, call the 988 Suicide and Crisis Lifeline.